The week ahead on General Hospital promises to shatter Port Charles to its very core. Monday’s episode (September 22, 2025) brings an unrelenting storm of grief, suspicion, betrayal,

and shocking revelations. What begins as quiet whispers in the hospital corridors soon spirals into a full-scale reckoning that will leave no family untouched.

Monica’s Death Sends Shockwaves Through Port Charles

The heartbreaking news breaks when Elizabeth Webber, her face pale and her hands trembling, delivers the announcement that Monica Quartermaine—the resilient matriarch of one of the most complex families in town—has passed away. For decades, Monica anchored the Quartermaines with her strength, wisdom, and fierce loyalty, but her sudden death casts a shadow of suspicion over the entire family.

Elizabeth informs Drew Cain of Monica’s passing, but Drew’s response is far from what many expect. Instead of raw grief, a flicker of something colder darkens his eyes. Monica had once cast him out of the Quartermaine fold, stripping away his place in the family with cutting finality. Now, Drew’s silence masks dangerous calculations. Was Monica’s death natural, or part of a larger scheme? Some whispers even suggest Drew himself may have orchestrated her demise.

For Drew, Monica’s passing is less about loss and more about opportunity. If foul play is at hand, it could be the opening move in a much bigger game of power within the Quartermaine dynasty.

Danny Pleads for Scout

The fallout spreads when Danny Morgan arrives, desperate to secure a place for his cousin Scout Cain—Monica’s granddaughter—at the funeral. Danny believes Scout has every right to honor her grandmother, but Drew refuses. His hardened stance reveals a desire to sever Scout’s ties to the family altogether.

Danny, frustrated and out of options, makes a desperate gamble. He offers Drew a secret—one powerful enough to shift the balance—if only Drew will allow Scout to attend the funeral. The tension in Drew’s silence suggests the stakes of Danny’s bargain could change everything.

Lulu’s Haunting Vision

Meanwhile, tragedy strikes in another corner of town. Lulu Spencer places a frantic 911 call after witnessing a devastating accident. When Harrison Chase arrives at the scene, Lulu insists she saw the victim’s face—and it was none other than Nathan West.

The revelation leaves Chase shaken. Nathan has been dead for years, his loss mourned by friends and family. Could Lulu’s grief be playing tricks on her mind, or has the impossible become real? Lulu clings to what she saw, sparking speculation that Nathan’s return may not be a miracle, but a curse that reopens old wounds and dangerous secrets.

Jason’s Quiet Grief and a Chilling Letter

Back at the hospital, Jason Morgan reels from the news of Monica’s death. Unlike Drew, Jason’s grief is heavy and silent, filled with regret over moments left unshared. Yet his sorrow quickly collides with a chilling discovery: a sealed letter from Monica, its edges marred by what looks like dried blood.

Inside, Monica reveals a secret that shakes Jason to his core—he and Drew’s mother is alive, and she may already be on her way to Port Charles. This revelation could upend everything the Quartermaines thought they knew about their family’s history.

Jason struggles with whether to share the letter’s contents, knowing its implications could rip open long-buried family fractures at a time when the Quartermaines are already on the brink of collapse.

Tracy Takes Control

As always, Tracy Quartermaine steps into the practical role, orchestrating Monica’s funeral arrangements with her trademark efficiency. Beneath her brisk demeanor, however, lies deep sorrow. She knows the ceremony is not only a farewell to her sister but a prelude to the Quartermaines’ unraveling.

Michael’s Anger Erupts

Elsewhere, Michael Corinthos grapples with his own emotional storm. Though he arrives at the mansion to support Jason, his simmering fury toward Willow Tate boils over at home. Michael’s anger, fueled by grief and fear of losing his children, explodes into declarations that Willow will never gain custody. His outbursts leave Willow shaken, uncertain of the man Michael is becoming.

Michael’s instability threatens to ignite a new family war just as the Quartermaines are reeling from loss.

Anna and Laura at Odds

At the same time, Anna Devane follows her instincts, convinced that the attack on Judge Eva Herron and the shooting of Drew are connected. She traces patterns in the crimes, but Laura Collins pushes back, suggesting multiple attackers may be working separately—or worse, using each other’s crimes as cover.

The debate leaves both women unsettled. If Anna is correct, one mastermind is pulling the strings. If Laura is right, Port Charles may be facing a network of enemies far more dangerous than anyone imagined.

The Shadow of Sonny Corinthos

As theories swirl, Sonny Corinthos and Brick remain in the shadows. Their silence is deafening, their strategic moves calculated, but suspicion lingers. Are they pawns in someone else’s deadly game, or architects of chaos themselves?

A Glimpse of Joy Amid Darkness

Not every storyline is soaked in grief. Molly Lansing Davis finalizes her decision to return Outback the dog to Gio Palmieri and Emma. Their reunion brings fleeting happiness, and the two share an intimate moment that contrasts the larger chaos engulfing Port Charles. But in this town, peace is always temporary.

The Funeral Looms

As Monica’s funeral draws near, tensions soar. Drew weighs Danny’s bargain. Jason carries the burden of Monica’s bloodstained letter. Michael struggles with his fury toward Willow. Lulu remains haunted by Nathan’s face. And Anna and Laura’s conflicting theories only deepen the uncertainty.

When mourners gather, suspicion hangs heavy in the air. Was Monica’s death truly natural, or a carefully orchestrated act? Every glance exchanged among the Quartermaines feels charged, every whisper laced with doubt.

The funeral is meant to honor Monica’s life, but instead it sets the stage for secrets to surface, alliances to fracture, and betrayals to be laid bare.

What Comes Next

By episode’s end, the question is no longer how Port Charles will mourn Monica—it is how her death will ignite the next phase of battles across the town.

Will Jason reveal the truth about his and Drew’s mother? Will Danny’s secret be powerful enough to sway Drew? Is Nathan truly alive, or a specter haunting Lulu? And who, if anyone, is orchestrating the web of violence that continues to tear through the city?

The storm is only beginning. Monica may be gone, but her shadow lingers over every storyline, every family, and every decision. And as Port Charles braces for what’s next, one thing is certain: the most dangerous secrets have yet to surface.