The latest General Hospital spoilers for Wednesday, November 5, 2025, promise a storm of betrayal, revenge, and haunting revelations that shake Port Charles to its core.

Misunderstandings and secrets run deep, leaving every character questioning whom they can trust — and who’s pulling the strings behind the chaos.

A Tense Morning in Port Charles: Drew Confronts Sonny and Alexis

The day begins in the dim light of Charlie’s Pub, where Alexis Davis sits across from Sonny Corinthos, their hushed tones carrying the weight of unfinished business. What starts as a discreet conversation quickly explodes into confrontation when Drew Kane walks in. The sight of Alexis and Sonny together stops him cold — his instincts screaming betrayal.

Sonny’s face hardens, his usual calm replaced by wary calculation, while Alexis scrambles to explain that their meeting is innocent. But Drew, worn thin from weeks of disappointment and failed plans, doesn’t believe her. Suspicion consumes him. His trust — once unshakeable — begins to fracture.

When Sonny finally breaks the silence, his words cut through the tension like a knife. He warns Drew to stop targeting the Corinthos family, especially Michael. The message is clear — cross the line again, and Sonny will no longer consider him an ally. The warning isn’t shouted; it’s delivered with quiet menace that lingers even after Sonny walks out, leaving Alexis and Drew standing in the ruins of their strained friendship.

Alexis, furious, accuses Drew of losing himself to revenge. She reminds him that he’s risking everything — Willow’s freedom, his daughter Scout’s safety, and his own soul — for a war that’s consuming him. Drew’s reply is chillingly calm: he’s done waiting, and he’ll take down every member of the Quartermaine family until he stands alone. His obsession has replaced his reason, and Alexis realizes the man before her may be beyond saving.

Hospital Showdown: Portia and Jordan’s Explosive Confrontation

Meanwhile, across town at General Hospital, a private argument between Portia Robinson and Jordan Ashford spirals into a fiery confrontation that echoes down sterile hallways. Portia accuses Jordan of stealing her husband, Curtis Ashford — of disguising seduction as friendship.

Jordan fires back, her composure slipping as old wounds reopen. She tells Portia she forfeited any claim to Curtis the moment she stopped fighting for him. But when Jordan coldly suggests that Curtis might not even be the father of Portia’s daughter, the air seems to freeze. The accusation hits its mark — Portia’s silence is all the confirmation Jordan needs.

Curtis, weary of deceit and betrayal, decides he’s done. He won’t seek revenge; he just wants peace — and that peace may only come through divorce. Portia is left reeling, realizing too late that she’s lost more than just her husband — she’s lost the illusion of control she once wielded so confidently.

Britt’s Dark Secret: Trapped by Sidwell’s Shadow

Far from the hospital’s chaos, in the cold, humming corridors of a secret research lab, Dr. Britt Westbourne faces her own torment. The brilliant but haunted physician has become a prisoner to Jyn Sidwell — a manipulative figure who holds her life in his hands.

Sidwell controls the only medication that keeps Britt’s mysterious illness at bay, forcing her to complete his unethical research project known only as “Project Zeta.” Every experiment she conducts, every falsified report she signs, eats away at her conscience.

When Jason Morgan unexpectedly visits the lab, tension sparks instantly. His eyes fall on young Rocco Falconeri, standing awkwardly nearby, and suspicion floods his face. To Jason, it looks like Britt is manipulating the boy — reopening old wounds tied to Rocco’s tumultuous past.

Britt insists she’s innocent, that Rocco came on his own. But Jason’s trust has long since burned out. He warns her to stay away from the boy and storms out, leaving Britt shaken. Only later does she realize her nightmare is far from over — Rocco has stolen her keycard, slipping it from her desk while her back was turned.

When Britt confronts Sidwell, her fury barely hides her fear. She accuses him of using the child to do his bidding, but Sidwell only smirks, reminding her that she’s in no position to ask dangerous questions. His cryptic words confirm what Britt has long suspected — she’s merely a pawn in a much larger game.

Tracy Quartermaine’s Ruthless Retaliation

At the Quartermaine estate, Tracy’s icy determination takes center stage. Furious over the forged will that nearly cost her family its fortune, she prepares a legal strike against Drew Kane, Martin Grey, and their accomplice, Ronnie Barr.

For Tracy, this isn’t just about justice — it’s about vengeance cloaked in righteousness. Ronnie, the weakest link, breaks under interrogation, confessing to everything and implicating Drew. Meanwhile, Martin braces for impact, knowing Tracy’s reach is long and her wrath unrelenting.

When Mayor Laura Collins learns of the charges, she tries to reason with Tracy, pleading for leniency. But Tracy is unmoved. Mercy, she declares, is for those who haven’t betrayed her. The Quartermaines will not be humiliated again.

That night, Martin signs his confession, his hand trembling as Laura watches from behind the glass. Their brief exchange — a silent promise of loyalty despite defeat — adds a rare moment of tenderness amid the unraveling chaos.

Anna Devane’s Chilling Abduction

As night falls, Port Charles sinks deeper into mystery. In an abandoned warehouse miles away, Anna Devane regains consciousness — bound, bruised, and terrified. Her instincts tell her this is no random kidnapping. Every detail, from the sterile silence to the faint hum of machinery, feels deliberate.

Through flashes of memory, she recalls a struggle, a familiar voice, the smell of gasoline. Somewhere beyond the walls, she hears the faint click of a camera — someone is watching her. Recording her. This isn’t about ransom; it’s about control.

Anna quickly realizes her abduction is connected to something larger — the same network behind Britt’s secret project and the forged will scandal. Someone is manipulating every major player in Port Charles, weaving their lives into a single, dangerous web.

Back in town, Sonny learns of Anna’s disappearance and feels the chill of unease. He senses the balance of power shifting again, though he doesn’t yet see how close the danger truly is. Alexis, upon hearing the news, suspects the same — that Drew’s reckless war and the city’s shadow dealings are converging into one catastrophic event.

The Cliffhanger: Port Charles on the Edge

By the end of the episode, every storyline collides in quiet suspense.

• Alexis sits alone, haunted by guilt.
• Portia replays her confrontation, realizing she’s lost Curtis for good.
• Britt stares in horror at a message from an unknown number — a grainy photo of Anna tied to a chair, alive but terrified.

No words. No demands. Just proof that someone holds all the cards.

As Laura gazes over the Port Charles skyline, she senses the corruption spreading like wildfire. And in the darkness beyond, Sonny stands at the edge of the pier, aware that the city he rules is slipping beyond his control.

What no one yet knows is that Anna’s abduction is only the beginning. Port Charles is heading toward a reckoning — one that will expose alliances, betrayals, and the true puppet master pulling every string.

And when the truth finally emerges, not everyone will make it out alive.